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Combined supplements lowered an inflammation score in healthy older adults

Healthy, active older adults receiving combined supplements had a lower inflammation score than placebo recipients. The abstract does not establish whether this translated into better health.

By 100HP editorialAbstract-based explanation checked

Based on the published abstract. The full paper may contain additional methods, results and limitations.

The 30-second takeaway

The supplement combination lowered a score combining inflammation markers compared with placebo after researchers adjusted for several participant characteristics. Nutrient-status markers also increased. The abstract gives no size for the inflammation-score difference or evidence of improved symptoms or disease outcomes, so this result concerns measured markers rather than a demonstrated health benefit.

Keep in mind

The abstract reports statistical significance without the inflammation-score difference or its confidence interval. Its healthy, active participants limit how directly the findings apply to older adults with different health circumstances.

THE RESULT, WITH CONTEXT

What researchers found

Lower INFLA score

Combined inflammation-marker score

Supplement combination versus placebo over 12 weeks, in an adjusted analysis; the score difference and its confidence interval were not reported.

Nutr Res, 2025 · Original source ↓

What the score represents

Researchers combined several inflammation markers into a single score. That summarizes laboratory measurements, but a change in the score does not itself describe how participants felt, functioned, or whether they developed an illness.

Who showed larger changes

Larger score decreases were reported among older participants and those whose starting diets scored as more inflammatory. These subgroup patterns describe variation within this trial; they do not establish who should receive the supplement combination.

CHECK THE ORIGINAL

The original publication

Multimicronutrient and omega-3 fatty acid supplementation reduces low-grade inflammation in older participants: An exploratory study.

Kerlikowsky F, Krüger K, Hahn A et al.
Nutr Res · 2025

PubMed ID
40644954
Record checked

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