Resistance training and DHA study tracks muscle quality and blood markers
In postmenopausal women with overweight or obesity, researchers reported muscle-quality improvements and changes in circulating proteins after training, DHA-rich supplementation, or both.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
The study reported improved muscle quality with resistance training or DHA-rich supplementation, alongside changes in blood markers related to muscle and inflammation. Supplementation also improved unspecified cardiometabolic markers. These are measurements of function and biological processes; the abstract reports no cardiovascular event outcomes, so it does not demonstrate that supplementation prevents heart disease.
The abstract omits sample size, allocation methods, supplement dose, and numerical effect estimates. It also does not explain how muscle quality was measured, making the size and practical importance of the changes difficult to judge.
Associations are separate from treatment effects
Before treatment, some circulating proteins were associated with body fat, insulin, and insulin resistance. These baseline correlations describe relationships between measurements; they do not show that altering a particular protein would improve muscle or cardiovascular health.
The combination remains uncertain
The study reported no statistical interaction between treatments. That does not establish that combining them is equivalent to either alone, and the abstract gives no interaction estimate or uncertainty range with which to judge this result.
The original publication
Myokine Circulating Levels in Postmenopausal Women with Overweight or Obesity: Effects of Resistance Training and/or DHA-Rich n-3 PUFA Supplementation.
Martínez-Gayo A, Félix-Soriano E, Ibáñez-Santos J et al.
Nutrients · 2025
- PubMed ID
- 40806137
- Record checked
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