Dietary vitamin K and fractures: possible association, uncertain evidence
Pooled estimates leaned toward lower fracture risk with greater intake, but neither overall nor hip-fracture results clearly excluded no association.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
Higher dietary vitamin K intake was linked to a trend toward fewer fractures, but the pooled estimates for overall and hip fractures remained statistically uncertain. Both confidence intervals included no association. This review therefore does not establish that increasing dietary vitamin K prevents fractures or provide an intake target for individuals.
This abstract-based assessment lacks follow-up durations, precise intake comparisons and the evidence-certainty ratings. The findings concern dietary intake, so they cannot establish the effects of taking vitamin K supplements.
What researchers found
Risk ratio for overall fractures
Across dietary vitamin K intake levels; exact groups and follow-up not reported. This ratio compares relative, not absolute, risk. One means equal risk; values below one suggest lower risk, but the interval includes one.
Suggestive but inconclusive
The review considered fractures overall and hip fractures separately. Both pooled estimates leaned toward lower risk with higher intake, but neither confidence interval excluded an absence of association, leaving the central finding inconclusive.
The intake pattern
A separate dose-response analysis suggested a U-shaped association between intake and fracture risk. The abstract gives no uncertainty estimates for this curve, so it cannot establish a reliable intake target.
The original publication
Dietary Vitamin K Intake and Fracture Risk: A Systematic Review and Dose-Response Meta-Analysis on the Interplay with Vitamin D.
Haghighat MML, Haghpanah B, Milajerdi A
Curr Rheumatol Rev · 2026
- PubMed ID
- 40947710
- Record checked
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