A benign thyroid nodule showed contrasting signals on paired scans
A case report described strong FDG uptake but more moderate octreotide-tracer uptake in a thyroid nodule later confirmed as benign.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
The thyroid nodule showed markedly different uptake with the imaging tracers, yet tissue examination confirmed a benign oncocytic thyroid adenoma. This illustrates an imaging pattern in an individual patient. It does not establish how accurately paired scans distinguish benign from malignant nodules, or whether they improve diagnosis across patients.
This abstract-based report describes an individual case and gives no diagnostic-accuracy results or comparison group of patients. It cannot establish reliable diagnostic criteria for thyroid nodules.
What researchers found
Maximum standardized tracer uptake (SUVmax)
FDG versus octreotide tracer in the same thyroid nodule during simultaneous PET/CT assessment; a descriptive case comparison without a diagnostic-accuracy estimate.
Signals and diagnosis
The scans measured tracer uptake and the volume of tissue showing uptake. Tissue examination supplied the diagnosis. Different scan signals in this case therefore should not be treated as separate diagnoses or measures of cancer severity.
The wider clinical course
Cortisol remained elevated after surgery, and later removal of a pituitary lesion identified a pituitary tumor. That clinical course is part of the case history, not evidence that the thyroid imaging explained the hormonal disorder.
The original publication
Dual-tracer 18F-FDG and 18F-AlF-NOTA-octreotide PET/CT imaging in oncocytic thyroid adenoma: a case report and literature review.
Li J
Front Endocrinol (Lausanne) · 2025
- PubMed ID
- 40951440
- Record checked
AI-assisted research and writing. This explains one selected publication; it is not a complete review of everything known. Our approach.
One more question, understood.
Keep track of the research you’ve explored.