Juvenile fibromyalgia treatments showed different effects on pain, function and mood
This brief summarizes the review's abstract, which reports uneven medication results and differing benefits from behavioral therapy and a program combining therapy with neuromuscular training.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
Medication trials reported modest pain improvements, but benefits for function and mood were inconsistent and adverse effects were common. Cognitive behavioral therapy improved disability and depressive symptoms, with limited effects on pain or measured activity. Adding neuromuscular training appeared more favorable for pain and biomechanical function than cognitive behavioral therapy alone.
The abstract does not give effect sizes, adverse-event counts or follow-up lengths. This summary cannot establish how large or lasting the benefits were, and the authors call for larger, more rigorous trials.
Outcomes did not move together
The review considered pain intensity, disability, depressive symptoms, physical activity and adverse events. These outcomes showed different patterns, so an improvement in daily functioning should not be read as evidence of reliable pain relief.
What the integrated program added
The integrated program paired cognitive behavioral therapy with neuromuscular training. Its reported advantage concerned pain and biomechanical function; the abstract does not establish whether that advantage extended to every outcome or persisted over time.
The original publication
Management of Juvenile Fibromyalgia: A Level I Evidence-Based Systematic Review.
Migliorini F, Maffulli N, Memminger MK et al.
Med Sci (Basel) · 2025
- PubMed ID
- 41003152
- Record checked
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