Pleuran trial found fewer respiratory infections in children with recurring illness
Adding pleuran to vitamin D and zinc reduced infection counts in children selected for recurrent respiratory illness.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
In children prone to repeated respiratory infections, the pleuran-containing supplement group had fewer infections during the study than the group receiving vitamin D and zinc alone. This tests the added formulation in a selected pediatric population. It does not establish a benefit for all children, and the abstract does not report whether school absence improved.
The abstract does not clarify whether its infection-count figures are averages per child or define the accompanying variability measures. It also does not explain how incomplete follow-up was handled.
What researchers found
Total respiratory tract infections
Over 3 months, the group receiving pleuran with vitamin D and zinc had significantly fewer infections than the group receiving vitamin D and zinc alone.
What the comparison tests
Both groups received vitamin D and zinc, while the active product also contained pleuran. The comparison concerns adding that formulation, rather than comparing the full product with taking no supplement.
Safety during the study
Only mild adverse events were reported, and the authors described favorable tolerability. These observations cover the trial period and cannot establish safety with longer use or in children outside the studied population.
The original publication
Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial.
Jesenak M, Prokopova E, Bozensky J et al.
Adv Ther · 2025
- PubMed ID
- 41085920
- Record checked
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