Resistance training review finds blood-marker shifts in older adults
A review of trials found changes in inflammatory and neuroplasticity markers, while leaving their implications for everyday function and long-term health unresolved.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
Across randomized trials in older adults, resistance training was associated with shifts in circulating biomarkers: lower pro-inflammatory markers and higher anti-inflammatory and neuroplasticity markers. These are laboratory findings. The abstract does not establish that participants thought more clearly, developed fewer diseases, or experienced slower aging, and it does not identify an optimal personal training dose.
Control conditions and overall follow-up durations are not specified. Too few studies were available to analyze dose-response patterns for anti-inflammatory markers, and the summary does not establish clinical benefits.
What was measured
The researchers pooled blood-marker results and separately examined how program features related to those results across trials. Markers associated with inflammation and neuroplasticity moved in different directions, so their biological roles matter when interpreting the summary.
Training patterns remain research questions
The abstract links some training characteristics with larger biomarker changes. Those comparisons do not establish an optimal program for an individual, and the reported outcomes do not show whether memory, daily function or disease risk changed.
The original publication
Dose-response relationship of resistance training and the effects on circulating biomarkers of inflammation or neuroplasticity in older adults: A systematic review and meta-analysis.
Qipo O, Gajauskaitė G, Vints WAJ et al.
Ageing Res Rev · 2026
- PubMed ID
- 41086999
- Record checked
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