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Frailty affected 36.5% of maintenance hemodialysis participants in a review

The pooled estimate describes existing frailty among people receiving ongoing hemodialysis. Reported associations with health and social factors do not establish causes.

By 100HP editorialAbstract-based explanation checked

Based on the published abstract. The full paper may contain additional methods, results and limitations.

The 30-second takeaway

Frailty was common among the maintenance hemodialysis patients represented in this review. Older age, living alone, other illnesses and several physical or psychological measures were associated with frailty. These findings describe prevalence and related factors; they do not establish that changing any particular factor will prevent frailty or reduce adverse events.

Keep in mind

This abstract-based account lacks a confidence interval for prevalence and estimates of association size. The abstract also does not explain frailty definitions or clearly specify the direction of every reported nutritional and inflammatory association.

THE NUMBERS, WITH CONTEXT

What researchers found

36.5%

Pooled frailty prevalence

Among maintenance hemodialysis patients; descriptive estimate with no comparator. Assessment timeframes and a confidence interval are not reported.

Int Urol Nephrol, 2026 · Original source ↓

Prevalence describes existing frailty

The pooled percentage summarizes how common frailty was among participants in the included studies. It is not a measure of new cases over time, nor an estimate of how likely a particular patient is to become frail.

Associations leave practical questions

The review reports links with depression, weaker grip and sleep disorders, alongside social and medical factors. Without association sizes or clear information about how other factors were accounted for, the abstract cannot establish their relative importance.

CHECK THE ORIGINAL

The original publication

Frailty in maintenance hemodialysis: a systematic review and meta-analysis of prevalence and risk factors.

Xu Q, Tang M, Wang Y et al.
Int Urol Nephrol · 2026

PubMed ID
41145904
Record checked

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