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Small supplement trial reports changes in mood and cognitive tests

A plant-extract and mineral blend improved selected outcomes in stressed adults, with cognitive findings less consistent outside a stressful task.

By 100HP editorialAbstract-based explanation checked

Based on the published abstract. The full paper may contain additional methods, results and limitations.

The 30-second takeaway

In generally healthy adults who felt stressed, a blend of plant extracts, magnesium and chromium improved some mood, anxiety and cognitive test results in a placebo comparison. Cognitive findings were less consistent without a multitasking stressor. The abstract reports no sleep results, despite measuring sleep, and does not establish broader or lasting benefits.

Keep in mind

The analysed sample was small. The abstract does not explain the missing participant data or report effect sizes for the main outcomes, limiting judgments about how large or useful the reported changes were.

THE RESULT, WITH CONTEXT

What researchers found

Fewer subtraction errors

Attention and working-memory task performance

After an acute dose, the supplement improved this task outcome versus placebo; the abstract gives no effect size.

J Psychopharmacol, 2025 · Original source ↓

What participants did

In the blinded crossover trial, participants received both the supplement and placebo. Researchers assessed psychological well-being and sleep during treatment, and tested cognition after an acute dose and again following continued use.

What changed

Some attention and working-memory findings favoured the supplement, especially during an observed multitasking challenge. Mood disturbance, anger and anxiety scores also improved. No serious adverse effects were reported, which provides only limited information about safety.

CHECK THE ORIGINAL

The original publication

Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial.

Dodd F, Weishaupt R, Katumba PKM et al.
J Psychopharmacol · 2025

PubMed ID
41194549
Record checked

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