Researchers agree on shared outcomes for sleep trials in cognitive impairment
The project developed nine outcomes to help future trials measure comparable aspects of sleep and its daytime effects.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
The study proposed a shared set of outcomes for trials testing sleep interventions in people with cognitive impairment. Its main contribution is agreement about what future research should measure, including sleep, daytime sleepiness, cognition and mood. It does not establish whether any particular treatment improves sleep or other health outcomes.
The abstract does not give interview or panel sizes, the study timeline, or details of how each outcome should be measured. Agreement on outcomes alone cannot show that future trials will produce better evidence.
How outcomes were selected
A review identified 287 different sleep outcomes used in earlier trials. Interviews then brought in the priorities of people with cognitive impairment and caregivers, before an expert consensus process selected the shared outcome set.
What the set covers
The agreed measures cover sleep duration, time taken to fall asleep, wakefulness after falling asleep, awakenings and sleep efficiency. They also include overall sleep quality, daytime sleepiness, cognition and mood, bringing patient priorities into the measurement framework.
The original publication
Development of a core outcome set for clinical trials of interventions to improve sleep in people with cognitive impairment-the Sleep in Cognitive Impairment Core Outcome Set (SCICOS).
Crowley P, Henry AL, Flanagan E et al.
Alzheimers Dement · 2025
- PubMed ID
- 41198603
- Record checked
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