Pulmonary hypertension estimates varied by heart condition and diagnostic criteria
A review estimated how common pulmonary hypertension is in people with left heart disease, with results varying by diagnostic definition.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
The review found that estimates of pulmonary hypertension varied by heart condition and diagnostic definition. Its regional population figures were extrapolated from the reviewed evidence. These findings describe estimated disease burden in a particular setting and do not show whether detecting or treating pulmonary hypertension improves health outcomes.
The population figures are extrapolations, and the abstract does not report the timeframes of the underlying studies. Estimates depend on the cardiac conditions included and the chosen diagnostic framework.
What researchers found
Estimated population prevalence of pulmonary hypertension associated with left heart disease
“At-risk” versus “manifest” categories, respectively, in Austria, Germany and Switzerland in 2024; estimates were extrapolated.
How categories were defined
The researchers used blood-flow measurements from heart ultrasound and pressure measurements from heart catheterization to classify pulmonary hypertension. Estimates were lower under the stricter “manifest” definition than under the “at-risk” definition, showing why the diagnostic criteria matter.
From patients to population
The underlying studies concerned people with heart failure or selected valve disorders. Estimates within these patient groups describe a different population from the wider regional figures derived by extrapolation.
The original publication
The prevalence of pulmonary hypertension associated with left heart disease: a systematic review and meta-analysis.
Zeder K, Brown CH, Santi A et al.
Cardiovasc Res · 2025
- PubMed ID
- 41218085
- Record checked
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