PCOS supplement review found hormone changes but inconsistent menstrual results
A review of nutraceuticals reported changes in insulin and hormone measurements. Findings for ovarian follicle count and menstrual bleeding were inconsistent, leaving effects on menstrual health uncertain.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
Across the included studies, nutraceutical interventions were associated with lower fasting insulin and luteinizing hormone, alongside higher sex-hormone-binding globulin. These are laboratory measurements. Results for menstrual bleeding and ovarian follicle count were inconsistent, so the abstract does not establish more predictable periods or improved fertility, nor does it identify a reliably superior supplement.
The authors identify differences between studies and variable methodological quality. The abstract does not report treatment durations, comparator details or evidence-certainty ratings, limiting interpretation of the pooled laboratory results.
A broad supplement question
The review included randomized and quasi-experimental studies of products such as vitamin D, inositol and quercetin. Combining evidence across different products addresses a broad question about nutraceuticals, rather than a precise question about any single regimen.
Comparisons remain uncertain
The abstract describes vitamin D as having the strongest metabolic and hormonal results. Without direct comparative estimates or details of the underlying studies, that statement does not establish that vitamin D outperforms other options.
The original publication
The effect of nutraceutical interventions on reproductive health outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis.
Çelik ZM, Kurnaz D, Özcan A et al.
Diabetes Obes Metab · 2026
- PubMed ID
- 41287200
- Record checked
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