Olive oil comparison found vascular changes in people with high blood lipids
A post hoc analysis found differences in vascular measurements between oil regimens, without reporting cardiovascular events.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
In patients with high blood lipids, the higher-phenolic olive oil regimen produced a larger improvement in reperfusion rate and a larger reduction in systolic blood pressure than the lower-phenolic regimen. These were short-term measurement changes. Because oil concentration and dose changed together, the abstract cannot isolate which feature accounts for the differences.
This was a post hoc analysis, and all participants consumed olive oil. Comparisons with healthy controls therefore do not isolate olive oil's effect against receiving no oil; cardiovascular event outcomes were not reported.
What researchers found
Vascular reperfusion rate
After 4 weeks, the higher-phenolic, lower-dose regimen outperformed the lower-phenolic, higher-dose regimen among patients with high blood lipids; effect magnitude not reported.
What the vascular test measured
The primary endpoint assessed blood-vessel lining function using near-infrared spectroscopy. Reperfusion and oxygen consumption rates improved in patients compared with healthy controls, a different clinical group that also received olive oil.
How the oil regimens differed
Randomized patient groups received different polyphenol concentrations and amounts of oil, designed to deliver equal total polyphenols. The result concerns that paired regimen comparison, without separating concentration from the amount consumed.
The original publication
Extra Virgin Olive Oil (EVOO) Improves Vascular Endothelial Function and Hemodynamic Parameters in Patients with Hyperlipidemia: A Post Hoc Analysis of a Randomized Controlled Trial.
Kourek C, Makaris E, Benetou V et al.
Nutrients · 2025
- PubMed ID
- 41373940
- Record checked
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