Mitophagy research map tracks scientific attention, without testing treatments
A publication analysis charted growth, collaborations and emerging topics in research linking mitophagy with neurodegenerative diseases.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
This study mapped the research literature on mitophagy in neurodegenerative diseases. It found expanding publication activity and identified established and emerging themes, including work on potential therapeutic compounds. These results show where researchers have focused attention. They do not establish that changing mitophagy, or using any highlighted compound, improves symptoms, prevents disease or benefits patients.
Publication and citation patterns measure research activity, not treatment effectiveness. The analysis used selected literature databases and excluded the incomplete final year's records from growth modeling, while retaining them for other analyses.
What researchers found
Peak annual publication output
Compared across publication years in the analyzed literature; incomplete 2025 records were excluded from growth analyses. This was a bibliometric outcome.
What the map showed
Topic clusters emphasized Parkinson's disease, mitochondrial dysfunction, oxidative stress and related mechanisms. Emerging themes included gut microbiota and molecular regulation, alongside investigations involving curcumin and melatonin; these were research topics, not tested recommendations from this analysis.
How the evidence was used
Researchers analyzed publication records to trace the field's development and international collaborations. The United States led publication output, with institutions in the United States, United Kingdom and China forming central collaboration networks.
The original publication
Global trends and perspectives in mitophagy on neurodegenerative diseases: a scientometric analysis over 20 years.
Wu H, Zhang M, Zhang L et al.
Front Med (Lausanne) · 2025
- PubMed ID
- 41426598
- Record checked
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