Multivitamin trial in preeclampsia reports lower urine protein
Adding a multivitamin to magnesium sulfate lowered urine protein and some reported complications; blood pressure differences between groups were not statistically significant.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
Among pregnant women with preeclampsia, the multivitamin group had lower urine protein and fewer reported cases of bleeding after birth, low birth weight and newborn intensive care admission than the magnesium-only group. Blood pressure showed no statistically significant difference between groups. These results concern the clinical treatment setting studied.
The abstract does not report blinding, multivitamin ingredient amounts or how long maternal and newborn outcomes were tracked. This abstract-based summary cannot establish which ingredient contributed to the differences.
What researchers found
Protein in urine collected over 24 hours
After 2 weeks, multivitamin plus magnesium sulfate versus magnesium sulfate alone (P < 0.001). The abstract does not define ±.
Measurements and complications
The trial examined urine protein, placental blood flow and clotting tests alongside maternal and newborn complications. Laboratory and ultrasound findings describe different outcomes from complications experienced by mothers or babies.
Uncertain eclampsia result
Only the magnesium-only group had cases of eclampsia, but the comparison was not statistically significant. That leaves the treatment's effect on this outcome uncertain; it does not demonstrate prevention.
The original publication
Effects of multivitamin combined with magnesium sulfate versus magnesium sulfate alone on hemodynamics, coagulation, and maternal-infant outcomes in preeclampsia: a randomized controlled study.
Gao S, Ming J, Sun F et al.
J Health Popul Nutr · 2025
- PubMed ID
- 41476304
- Record checked
AI-assisted research and writing. This explains one selected publication; it is not a complete review of everything known. Our approach.
One more question, understood.
Keep track of the research you’ve explored.