Vitamin C and E review reports blood pressure and cholesterol changes
A trial review described similar effects on several risk markers, but its results do not establish which supplement approach works best.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
The review reported statistically significant reductions in systolic blood pressure with vitamin C and combined vitamin C plus E, and an HDL cholesterol increase with the combination. These results concern measured risk markers in diabetes. Significant findings for some approaches alone do not establish differences between approaches or show fewer clinical complications.
The abstract omits doses, treatment durations, control details, effect sizes and confidence intervals. It also describes systolic blood pressure effects as both comparable and differing, leaving the comparison unclear.
Which outcomes were studied
Researchers examined blood sugar control, blood lipids and blood pressure in people with diabetes. These measurements describe risk factors; the abstract does not report whether supplementation changed cardiovascular events or diabetes complications.
How to read the comparison
The authors described comparable effects on blood sugar control, diastolic blood pressure and lipids other than HDL. Without numerical comparisons, that wording cannot establish equivalence or show how large any differences between supplement approaches might be.
The original publication
Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis.
Aragón-Vela J, Huertas JR, Casuso RA
Nutr Rev · 2026
- PubMed ID
- 41521729
- Record checked
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