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Creatine pilot leaves soccer injury prevention uncertain

Strength and jump performance improved, but injury incidence and missed training differences were not statistically significant in this small placebo-controlled trial.

By 100HP editorialAbstract-based explanation checked

Based on the published abstract. The full paper may contain additional methods, results and limitations.

The 30-second takeaway

The trial did not establish that creatine prevents injuries in amateur soccer players. Although fewer injuries and missed training sessions were reported with creatine, neither difference reached statistical significance. Some strength measures and jump height improved relative to placebo, but those performance changes cannot substitute for evidence of an injury-prevention benefit.

Keep in mind

This abstract-based summary is limited by the pilot's small size, a wide confidence interval for injury risk, and conflicting participant totals in the methods and results. The injury estimate remains compatible with substantially different effects.

THE NUMBERS, WITH CONTEXT

What researchers found

Risk ratio 0.23 (95% CI 0.03–1.75)

Musculoskeletal injury incidence

Creatine versus placebo over 14 weeks: 8.3% versus 36.4%; p = 0.155. The difference was not statistically significant.

J Int Soc Sports Nutr, 2025 · Original source ↓

Injuries and performance answer different questions

Injury incidence and training availability were the main outcomes. Strength and jumping were secondary measures, so improvements in these tests answer a different question from whether players experienced fewer injuries or could attend more training.

The uncertainty remains substantial

The numerical injury difference favored creatine, but its confidence interval was wide and included no difference. That uncertainty means the pilot neither demonstrates reliable protection nor proves that creatine has no effect on injury risk.

CHECK THE ORIGINAL

The original publication

Effectiveness of a soccer injury prevention program based on creatine supplementation and internal load monitoring: a randomized controlled pilot study.

Soler Hurtado M, Treguier M, González-de-la-Flor Á et al.
J Int Soc Sports Nutr · 2025

PubMed ID
41704196
Record checked

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