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Oral health

Teeth, gums and the wider context of oral health.
Short explanations show the finding and its limits. Paper records link you to the source.

378 papers in this topic55 short explanations
Oral health2 min read

Review finds inconsistent oral microbiome patterns in autism

Studies reported mixed differences in mouth microbes, with no consistent connection to core autism symptoms. Findings about microbial pathways provide clues for further research.

Systematic review of 9 case-control and cross-sectional studies.2025
30-second takeaway

This review found an uneven picture of oral microbes in autism: some studies reported differences in microbial diversity, while others did not find statistically significant differences. There was also no consistent relationship with core autism symptoms. These observational findings do not show that mouth microbes cause autism or that changing them improves symptoms.

Keep in mind: The review drew on observational studies, which cannot establish causation. The abstract provides no pooled effect estimates or participant ages, limiting assessment of the size and applicability of reported differences.

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Abstract-based explanation

Oral health2 min read

Review examines melatonin added to nonsurgical care for periodontitis

A small meta-analysis reported a significant probing-depth difference, but missing comparison details prevent a clear interpretation of benefit.

Systematic review and meta-analysis using fixed-effects and random-effects models.2025
30-second takeaway

The review examined melatonin added to nonsurgical periodontal treatment and reported a statistically significant pooled difference in probing depth. However, the abstract does not identify the control treatment or explain which direction its standardized estimate favors. This limits what can be concluded about whether adding melatonin improved that measurement.

Keep in mind: Only 3 studies entered the meta-analysis. This abstract-based account lacks the risk-of-bias results, adverse-event information and details of melatonin dose and delivery, limiting interpretation of both benefit and safety.

Study details & source ↗

Abstract-based explanation

Oral health2 min read

Chewing training review finds improved tongue pressure

The pooled result concerned tongue pressure after gum exercises, leaving broader changes in chewing function uncertain from the abstract.

Systematic review and meta-analysis including 9 studies.2025
30-second takeaway

The review found higher tongue pressure after chewing-gum exercises, a result concerning a specific aspect of oral function. The abstract does not establish whether this translated into easier eating or broader health benefits. Participants and training methods varied, and the authors considered gum and hard chewing materials unsuitable for people without teeth.

Keep in mind: This abstract-based explanation lacks comparison groups, training duration, and participant details for the pooled tongue-pressure result. These omissions limit interpretation and its relevance to a particular person.

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Abstract-based explanation

Oral health2 min read

Mapping ferroptosis research in head and neck cancer

A bibliometric analysis charted publications, geographic contributors and recurring research themes. Its outcomes describe scientific activity rather than treatment effects or patient health.

Bibliometric analysis using publication mapping and visualization.2025
30-second takeaway

The analysis found that China contributed the largest share of publications on ferroptosis in head and neck cancer. It also identified recurring themes involving cell death, metabolism, inhibition and therapy. These findings describe where research attention is concentrated; they do not show that targeting ferroptosis improves cancer outcomes or establishes an effective treatment.

Keep in mind: This abstract-based account covers a publication analysis from a single database. Publication counts and frequent keywords cannot establish treatment effectiveness, study quality or clinical importance, and the abstract reports no patient outcome analysis.

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Abstract-based explanation

Oral health2 min read

Gum treatment was linked to changes in cardiovascular risk markers

A systematic review found improvements in selected inflammation and blood-sugar markers after nonsurgical periodontal treatment, with less consistent findings for blood vessels and lipids.

Systematic review of 16 studies, with risk of bias assessed for the included research.2025
30-second takeaway

Nonsurgical treatment for gum disease was associated with improvements in several laboratory markers related to cardiovascular risk. However, vascular findings varied, and lipid changes were inconsistent and generally modest. The abstract reports markers rather than heart attacks or other cardiovascular events, so it does not establish that treatment prevents those outcomes.

Keep in mind: The abstract does not specify study designs, comparison groups, effect sizes, or follow-up duration. These omissions limit assessment of causality and the clinical importance of the reported marker changes.

Study details & source ↗

Abstract-based explanation

Oral health2 min read

Neck treatments favored jaw pain relief; mouth-opening results were uncertain

A review found favorable pain results in muscle-related jaw disorders, but the overall mouth-opening result was not statistically significant.

Systematic review and meta-analysis of 14 randomized controlled trials.2025
30-second takeaway

Neck manipulation and therapeutic exercise showed favorable pooled results for jaw-area pain and pressure pain thresholds. The overall mouth-opening result remained uncertain. A subgroup receiving combined manipulation and exercise had a favorable mouth-opening result, but this does not establish that combining treatments is superior to manipulation alone.

Keep in mind: This abstract-based explanation lacks comparator details and follow-up timing. Treatments varied, and the authors call for larger, better-designed trials, leaving meaningful and lasting benefits uncertain.

Study details & source ↗

Abstract-based explanation

Oral health2 min read

Notch-related tumor markers were linked to prognosis in adenoid cystic carcinoma

A systematic review found associations between tumor markers and survival or recurrence, but differences in study methods restricted how much evidence could be pooled.

Systematic review with meta-analyses of studies using comparable methods.2025
30-second takeaway

Notch-related mutations and protein-expression markers were associated with survival or recurrence in adenoid cystic carcinoma. These findings suggest possible value for estimating prognosis, but they do not show that using these markers improves treatment decisions or patient outcomes. The abstract also leaves important details about comparison groups and statistical uncertainty unspecified.

Keep in mind: This abstract-based account cannot assess the precision of the reported associations: confidence intervals, follow-up periods and explicit reference groups for the hazard estimates are missing. The findings concern prognosis, without establishing a benefit from marker-guided care.

Study details & source ↗

Abstract-based explanation

Oral healthPaper record

Effectiveness of Fluoride Varnish in Preventing Dental Caries: Systematic Review and Meta-Analysis.

Meta-analysis · Curr Drug Res Rev · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Oral healthPaper record

Pediatric snakebite in Sub-Saharan Africa: Clinical predictors, outcomes, and gaps in care-A systematic review.

Systematic review · PLoS Negl Trop Dis · 2026. Source record refreshed; an explanation has not been reviewed.

Systematic review2026
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Oral healthPaper record

Antimicrobial effect of garlic-based mouthwash on dental caries-related oral microorganisms: A systematic review and meta-analysis.

Meta-analysis · Arch Oral Biol · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Oral healthPaper record

Metagenomics in the diagnosis of pneumonia: a systematic review.

Systematic review · Infect Dis (Lond) · 2026. Source record refreshed; an explanation has not been reviewed.

Systematic review2026
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Oral healthPaper record

The Effect of Probiotic Lactobacillus Strains on Porphyromonas gingivalis, the Etiological Factor of Periodontal Diseases-A Systematic Review.

Systematic review · Probiotics Antimicrob Proteins · 2026. Source record refreshed; an explanation has not been reviewed.

Systematic review2026
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Oral healthPaper record

The Impacts of Probiotics Supplementation on the Treatment of Periodontitis: An Umbrella Meta-Analysis.

Meta-analysis · Nutr Rev · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Oral healthPaper record

A Current Perspective of Two of the Most Aggressive Head and Neck Cancers: Pharyngeal and Laryngeal.

Systematic review · Curr Oncol · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Examining the relationship between empathy and burnout in dental students: a systematic review.

Systematic review · Evid Based Dent · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Inflammatory Association between Periodontal Disease and Systemic Health.

Systematic review · Inflammation · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

[Associations between salivary melatonin and periodontal disease: a systematic review and meta-analysis].

Meta-analysis · Stomatologiia (Mosk) · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Oral healthPaper record

Association between periodontal disease and Alzheimer's disease: umbrella review.

Systematic review · Front Dent Med · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Risk Factors of Periodontitis: Evidence From Two-Sample Mendelian Randomization and Meta-Analysis.

Meta-analysis · J Periodontal Res · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Oral healthPaper record

Association between cardiovascular diseases and apical periodontitis: An umbrella review with stratification of evidence and sensitivity analysis.

Systematic review · J Dent · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Bedside vs Conventional Operating Room Surgery in Critically Ill Newborns: Systematic Review and Meta-Analysis.

Meta-analysis · J Pediatr Surg · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Oral healthPaper record

The role of oral microbiota and tooth loss in cardiovascular disease risk: a systematic review.

Systematic review · Biofouling · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Impact of tracheostomy on ICU stay in adult patients with ARDS: A systematic review.

Systematic review · Intensive Crit Care Nurs · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Oral healthPaper record

Detection of carotid artery calcifications using artificial intelligence in dental radiographs: a systematic review and meta-analysis.

Meta-analysis · BMC Med Imaging · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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