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Skin

Skin health, care and changes with age.
Short explanations show the finding and its limits. Paper records link you to the source.

296 papers in this topic26 short explanations
Skin2 min read

Carotenoids and skin aging: a review maps possible protective mechanisms

The review brings together human and animal research, but its abstract does not quantify visible skin benefits or identify a proven product.

Systematic review of 176 studies, synthesized narratively rather than statistically pooled.2025
30-second takeaway

The review describes ways carotenoids may influence skin aging, including effects on oxidative damage, inflammation, and the skin’s structural support. It also discusses hydration and elasticity. However, the abstract combines human and animal evidence without separating their results, so it cannot establish how much a dietary or topical carotenoid would improve someone’s skin.

Keep in mind: The studies differed in design and outcomes, preventing pooled analysis. The abstract gives no separate human effect estimates, treatment durations, or detailed bias findings, limiting conclusions about practical skincare benefits.

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Abstract-based explanation

Skin2 min read

Collagen supplements favored skin hydration and elasticity in pooled trials

A review reported improvements in skin measurements, with uncertainty about study bias and how noticeable the changes were.

Systematic review and meta-analysis of 10 randomized controlled trials.2025
30-second takeaway

The pooled results favored oral collagen for measured skin hydration and elasticity. These findings suggest improvements in those specific measurements, but the abstract does not establish whether people noticed a difference in their skin. It also does not show that any particular dose works better than another.

Keep in mind: This abstract-based explanation cannot resolve unclear study bias or differences between studies. Most trials could not control weather-related factors, and the authors could not assess publication bias.

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Abstract-based explanation

SkinPaper record

Hibiscus Collagen Alternative (VC-H1) as an Oral Skin Rejuvenating Agent: A 12-Week Pilot Study.

Randomized controlled trial · Int J Mol Sci · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Semiparametric approach to estimation of marginal mean effects and marginal quantile effects.

Study design not specified in the source record · J Econom · 2025. Source record refreshed; an explanation has not been reviewed.

Study design not specified in the source record2025
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SkinPaper record

Effectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials.

Systematic review · Front Med (Lausanne) · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

The Effects of α-Linolenic Acid Intake on Skin and Blood Vessel Health and Subjective Fatigue in Middle-Aged Japanese Females: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative Trial.

Randomized controlled trial · J Nutr · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

The Role of Glutamine and Arginine in Wound Healing of Pressure Ulcers: A Systematic Review.

Systematic review · Wound Repair Regen · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Effect of Methotrexate on Semen Parameters in Psoriatic Male Patients.

Study design not specified in the source record · Cureus · 2025. Source record refreshed; an explanation has not been reviewed.

Study design not specified in the source record2025
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SkinPaper record

Clinical Trial of Salmon Nasal Cartilage-Derived Proteoglycans on Human Facial Antiaging: A Randomized, Double-Blind, Placebo-Controlled Study.

Randomized controlled trial · J Cosmet Dermatol · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Oral Collagen Oligopeptides as a Modulator of Skin Health: A Comprehensive Evaluation of Clinical and Molecular Effects.

Randomized controlled trial · J Med Food · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Non-Invasive Imaging for the Evaluation of a New Oral Supplement in Skin Aging: A Case-Controlled Study.

Randomized controlled trial · Skin Res Technol · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Skin Photoprotection and Anti-Aging Benefits of a Combination of Rosemary and Grapefruit Extracts: Evidence from In Vitro Models and Human Study.

Randomized controlled trial · Int J Mol Sci · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Psychosocial interventions for psoriasis: a Bayesian network meta-analysis.

Meta-analysis · J Dermatolog Treat · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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SkinPaper record

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Meta-analysis · Am J Med · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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SkinPaper record

A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial for the Efficacy and Safety of a Novel Nutraceutical for Mild-to-Moderate Acne.

Randomized controlled trial · J Cosmet Dermatol · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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SkinPaper record

Surgical strategy and outcomes of penoscrotal Paget's disease: A large retrospective cohort study in a Chinese tertiary center.

Cohort study (title) · Eur J Surg Oncol · 2025. Source record refreshed; an explanation has not been reviewed.

Cohort study (title)2025
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SkinPaper record

Off-Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives.

Systematic review · Exp Dermatol · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Systematic Review of Platelet-Rich Plasma and Platelet-Rich Fibrin in Facial Rejuvenation.

Systematic review · Ann Plast Surg · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Global, regional, and national burden of asthma and atopic dermatitis, 1990-2021, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021.

Systematic review · Lancet Respir Med · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Treatment of Solar Lentigines: A Systematic Review of Clinical Trials.

Systematic review · J Cosmet Dermatol · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Efficacy of platelet-rich plasma in facial rejuvenation: A systematic review.

Systematic review · Enferm Clin (Engl Ed) · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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SkinPaper record

Evidence-Based Recommendations for Managing Atopic Dermatitis in Pediatric Patients: A Systematic Review and Meta-Analysis From the Pediatric Dermatology Special Interest Group of IADVL.

Meta-analysis · Int J Dermatol · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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SkinPaper record

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.

Meta-analysis · Nutr Rev · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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SkinPaper record

Role of VDR gene polymorphisms and environmental factors in the development of skin cancers: evidence by updated meta-analysis.

Meta-analysis · Arch Dermatol Res · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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