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Vitamins, minerals and other supplemental compounds.
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2,705 papers in this topic217 short explanations
Supplements2 min read

Garlic tablets improved several metabolic markers in women with PCOS and metabolic syndrome

A short randomized trial reported favorable changes in blood sugar, lipids and other measures, but does not establish lasting clinical benefits.

Randomized placebo-controlled clinical trial.2025
30-second takeaway

Women receiving garlic tablets showed favorable changes in several metabolic measures compared with placebo, including fasting blood sugar and blood lipids. The trial also reported improvements in quality of life and sexual function. These findings apply to women with both PCOS and metabolic syndrome and do not establish prevention of diabetes or cardiovascular disease.

Keep in mind: The authors note short follow-up, limited dietary control and missing hormone tests. This abstract-based summary cannot establish persistence of the effects or translate marker changes into fewer future health problems.

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Efficacy of vitamin D supplementation in patients diagnosed with depression: a dose-response meta-analysis of randomized controlled trials.

Systematic review · Front Nutr · 2026. Source record refreshed; an explanation has not been reviewed.

Systematic review2026
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Effect of dietary nutrient supplementation on birth outcomes in pregnant women with gestational diabetes mellitus: A network metaanalysis.

Meta-analysis · Nutrition · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Impact of creatine supplementation on inflammation: evidence from a systematic review and meta-analysis of randomized double-blind placebo trials.

Meta-analysis · Front Immunol · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Preventing Hand-Foot Syndrome in Patients With Cancer: A Systematic Review and Network Meta-Analysis.

Meta-analysis · JAMA Dermatol · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Anti-inflammatory effects and safety of omega-3 fatty acids in haemodialysis: A systematic review and meta-analysis.

Meta-analysis · Clin Nutr ESPEN · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Effect of Vitamin D Supplementation on Cardiometabolic Outcomes in Older Australian Adults-Results from the Randomized Controlled D-Health Trial.

Randomized controlled trial · Nutrients · 2026. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2026
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Marine n-3 fatty acid treatment for carotid plaques in patients with type 2 diabetes.

Randomized controlled trial · Cardiovasc Diabetol · 2026. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2026
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Preoperative Testosterone Replacement Therapy Is Associated With Increased Complication Risk After Total Hip Arthroplasty: A Propensity-Matched Analysis of Real-World Data.

Study design not specified in the source record · J Arthroplasty · 2026. Source record refreshed; an explanation has not been reviewed.

Study design not specified in the source record2026
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Melatonin Use in Young Children: A Systematic Review.

Systematic review · JAMA Netw Open · 2026. Source record refreshed; an explanation has not been reviewed.

Systematic review2026
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Effects of tetrahydroindenoindole supplementation on metabolism: A systematic review with meta-analysis of rodent-based studies.

Meta-analysis · Geroscience · 2026. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2026
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Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.

Meta-analysis · Nutrients · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Efficacy of Momordica charantia in glycaemic control and insulin resistance among patients with prediabetes and type 2 diabetes. A GRADE-adherent meta-analysis of randomised controlled trials.

Review · Metabol Open · 2025. Source record refreshed; an explanation has not been reviewed.

Review2025
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Efficacy of curcumin/turmeric on inflammation and oxidative stress in prediabetes and type 2 diabetes: a systematic review and dose-response meta-analysis.

Meta-analysis · Inflammopharmacology · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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[Dietary supplements for dry eye disease].

Systematic review · Ophthalmologie · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Vitamin D deficiency and depression in South Asian adults: A systematic review and meta analysis.

Letter · Asian J Psychiatr · 2025. Source record refreshed; an explanation has not been reviewed.

Letter2025
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Dysregulation of melatonin rhythm in Parkinson's and Huntington's disease: a systematic review and meta-analysis.

Systematic review · Front Aging Neurosci · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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Effects of spirulina (Arthrospira) platensis supplementation on inflammation, physical and mental quality of life, and anthropometric measures in patients with relapsing-remitting multiple sclerosis (RRMS): a triple-blinded, randomized, placebo-controlled trial.

Randomized controlled trial · Nutr J · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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Dietary β-Carotene, Vitamin A, and Retinol Intake and Prevalence of Colorectal Adenoma: A Cross-Sectional Study and Meta-Analysis.

Meta-analysis · Gut Liver · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.

Meta-analysis · Front Immunol · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Curcumin supplementation improves the clinical outcomes of patients with diabetes and atherosclerotic cardiovascular risk.

Randomized controlled trial · Sci Rep · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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Dietary and Circulating Vitamins, Polymorphisms of Vitamin Metabolism Genes, and the Risk of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.

Meta-analysis · Clin Transl Gastroenterol · 2025. Source record refreshed; an explanation has not been reviewed.

Meta-analysis2025
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Acute creatine supplementation enhances technical performance in adolescent basketball players under cognitive-motor dual-task condition.

Randomized controlled trial · J Int Soc Sports Nutr · 2025. Source record refreshed; an explanation has not been reviewed.

Randomized controlled trial2025
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Creatine Supplementation in Combat Sport Athletes: A Narrative Systematic Review.

Systematic review · J Diet Suppl · 2025. Source record refreshed; an explanation has not been reviewed.

Systematic review2025
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